CRYO-TRANSMISSION ELECTRON MICROSCOPE (Cryo-TEM)

Hitachi HT7800 TEM brand transmission electron microscope, which is in service at our center, provides high contrast and high resolution with its multiple lens configurations and allows for many specialized applications. The device can operate up to 120 kV accelerating voltage and provides the elemental analysis of the samples with the EDS detector that can scan the Boron-Uranium (5B-92 U) elemental range. Dual-Mode lens lenses in the device provide high contrast and resolution in all areas, even in low magnifications. Furthermore, thanks to the advanced stage navigation function, the entire grid is quickly scanned and the desired zone is easily detected at the desired magnifications.

The attachments that allows the cryogenic device, thanks to our work is the first and only in Turkey in this field. The most important advantage of cryo-TEM, which is popular in the world and especially in the field of structural biology, is that it allows the biomolecules to be seen in a lot of processes which cannot be observed before by freezing while they are in motion. On the other hand, in conventional TEM examinations, the problems such as radiation damage and high vacuum in the column, for example, are greatly exceeded by cryo-TEMs. Thus, it is possible to examine the samples with much less damage.

Analyzes:

• Ultrastructural investigations of all biological samples,
• Chemical and structural characterization of nanomaterials,
• Structure investigations of semiconductors,
• Morphological researches,
• Polymeric and glassy materials,
• Energy technology studies,
• Lightening of 3D structures of cells and tissues,
• Investigation of viruses and macromolecular complexes.

CRYO-TEM Device: Hitachi HT7800